Aug 12, 2009 (CIDRAP News) – A task force of the Institute of Medicine (IOM), charged with making recommendations about how to protect healthcare workers against novel H1N1 influenza, today heard a variety of evidence that respirators and masks can shield healthcare workers (HCWs) and others from getting respiratory illnesses.The IOM panel learned, for example, that N95 respirators—whether fit-tested or not—reduced respiratory illnesses in a recent multiple-hospital study in China, whereas surgical masks were not effective. But other studies, focusing on household transmission of flu, suggested that both surgical masks and N95-type respirators are valuable.Still another study, involving students at the University of Michigan, suggested that the combination of surgical masks and hand sanitizers may reduce the risk of respiratory illness, but the results didn’t achieve statistical significance.The committee also heard about the problems that some HCWs have with face protection—including a concern among pregnant HCWs in Singapore that wearing an N95 may cause fetal hypoxia.Evidence on the clinical effectiveness of personal protective equipment (PPE) has been notoriously fuzzy. In the face of the murky science, the IOM has been asked to provide a recommendation to the Centers for Disease Control and Prevention (CDC) and the Occupational Safety and Health Administration (OSHA) by Sep 1.The CDC currently recommends that HCWs who enter the room of a patient in isolation for suspected or confirmed novel H1N1 flu should wear an N95 respirator or equivalent protection.Today’s day-long workshop, which was streamed over the Web, was dedicated to examining what’s known about H1N1 flu and about the effectiveness of masks, gowns, gloves, respirators, and eye protection in preventing H1N1 and seasonal flu transmission.Hospital study in ChinaIn an afternoon session on preventing flu transmission with PPE, Raina MacIntyre of the University of New South Wales presented a few findings from an as-yet-unpublished study of respiratory protection in hospital workers in Beijing.The study compared the effectiveness of surgical masks, fit-tested N95 respirators, and non-fit-tested N95s in protecting HCWs from respiratory illnesses. The trial involved 1,936 workers in 24 hospitals, including physicians and nurses, who wore the equipment for 4 weeks last winter. The Chinese location was chosen because the team wanted a site where workers are used to wearing protection, making for high compliance, MacIntyre said.The researchers looked at several outcome measures, ranging from clinical respiratory illness and influenza-like illness (ILI) to lab-confirmed flu.She said she the detailed results of the trial are being saved for a meeting in September and journal publication, but she revealed a few findings: An intention-to-treat analysis showed that the surgical masks had no efficacy against any outcomes, whereas the N95s provided 75% protection against lab-confirmed flu. She also said the N95s were 42% more effective than the surgical masks overall.MacIntyre also reported that the fit testing did not improve the effectiveness of the N95s, as there was no difference between the results for the fit-tested and non-fit-tested groups.Household transmission studiesMacIntyre also reviewed the findings of a recent study that compared the use of surgical masks and P2 respirators (the equivalent of N95s) in households where a child was diagnosed with a respiratory illness. The randomized controlled trial was reported in Emerging Infectious Diseases in February.The Australian researchers recruited 145 families, who were assigned to wear surgical masks, P2s, or no respiratory protection. The outcome measures were ILI and confirmed respiratory virus infections.The scientists found no difference in illness rates between the P2 and surgical mask groups overall. However, mask use in the intervention groups was fairly low, and when the team looked only at the families that actually used the respiratory protection, they found a four-fold reduction in clinical illness for both groups, MacIntyre reported. No clear difference between the P2 and surgical mask groups was found.A somewhat similar study, recently published in the Annals of Internal Medicine, was reviewed by Ben Cowling of the University of Hong Kong. He and his team used rapid flu tests to recruit patients from outpatient clinics and then studied the effects of interventions in their households.The researchers recruited about 250 households and divided them into three groups: basic health education only, hand hygiene with soap and an alcohol hand rub, and hand hygiene plus surgical face masks.The study produced some evidence that the interventions made a difference in flu transmission, but it varied depending how soon the interventions were initiated, Cowling reported.Overall, 10% of contacts in the control group households contracted confirmed flu, versus 5% of contacts in the hand hygiene group and 7% in the hand hygiene plus face masks group. In a subanalysis focusing on households where interventions were started within 36 hours of the index patient’s illness onset, the respective proportions were 12%, 5%, and 4%.Cowling concluded, as stated in a slide, that the study showed “substantial and significant benefits of face masks and hand hygiene if implemented within 36 hours of index case symptom onset.” He said it wasn’t possible to distinguish which of the two interventions was more effective.Pregnant women and N95sThe panel also heard Paul Ananth Tambyah of Singapore National University hospital review the SARS (severe acute respiratory syndrome) experience at his hospital, where full PPE, including N95s and gowns, was found to provide good protection.In a question period, Tambyah revealed that pregnant HCWs in Singapore do not wear N95s. They are exempted from the requirement because gynecologists believe there will be fewer incidents of fetal hypoxia if pregnant workers don’t use the devices, he said. Pregnant women appear to be at increased risk for complications from novel H1N1 flu.”I think the general consensus with university obstetricians is to use surgical masks rather than N95s” in pregnant women, except when they are involved in intubation or other aerosol-generating procedures, Tambyah said.Dr. Howard J. Cohen, a member of the IOM panel, commented later that, assuming the concern about fetal hypoxia is valid, “It seems the solution is to put them in a PAPR [powered air purifying respirator], where they have plenty of room to ventilate.”See also: IOM page on workshophttp://nationalacademies.org/hmd/activities/workforce/respproth1n1/2009-…IOM page with link to meeting agendahttp://nationalacademies.org/hmd/Activities/Workforce/RespProtH1N1/2009-…Current CDC recommendations for infection control for care of H1N1 patientshttp://www.cdc.gov/h1n1flu/guidelines_infection_control.htm
Tag: 夜上海论坛QZ Moyes reveals Ronaldo wish
Moyes watched Ronaldo’s awesome performance for Portugal in their World Cup play-off victory over Sweden in Stockholm on Tuesday on TV. Like everyone else who witnessed the winger’s hat-trick, the United boss was spellbound by the talent Ronaldo displayed so regularly during his six seasons with the Red Devils. Indeed, there was intense speculation during the close season Ronaldo was intent on heading back to his old club, with United eager to make a marquee signing to herald the arrival of Moyes as Sir Alex Ferguson’s successor. It did not happen. And now he has signed a five-year contract with Real Madrid, and declared his intention to remain at the Bernabeu for the remainder of his career, it seems highly unlikely it ever will. However, maybe clinging to the most slenderest of hopes, Moyes is not giving up completely. “Everyone at Manchester United would tell you he is the best in the business anyway,” Moyes told MUTV. “I have not been fortunate enough to work with him but there is still hope some day it might be possible.” Press Association Manchester United manager David Moyes has not given up on the possibility of working with Cristiano Ronaldo one day.
Daragh’s amazing pictureA super moon deserves a super picture.And we doubt if you’ll find many better than Daragh McDonough’s wonderful offering.Daragh took the picture at the Dry Arch Roundabout outside Letterkenny on Sunday evening last. We’re not sure how long he waited to capture the image or if he done his homework on the moon’s position beforehand.But it’s a wonderful image which doesn’t come along too often – perhaps just once in a super moon!Many thanks for sharing it with us Daragh.THE TINNEYS CARRY HOME THE SUPER MOON – PICTURE SPECTACULAR! was last modified: August 13th, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Daragh McDonoughdonegalDry Arch RoundaboutletterkennypictureSuper moon